Markus Christmann Selected Research

O-(6)-methylguanine

4/2022	Senescence Is the Main Trait Induced by Temozolomide in Glioblastoma Cells.
7/2021	Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide Treatment.
1/2019	DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas.
1/2013	Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage.

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Markus Christmann Research Topics

Disease

35	Neoplasms (Cancer) 03/2024 - 05/2002
17	Glioma (Gliomas) 01/2022 - 12/2007
15	Glioblastoma (Glioblastoma Multiforme) 03/2024 - 07/2009
7	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2018
4	Brain Neoplasms (Brain Tumor) 04/2022 - 07/2009
4	Melanoma (Melanoma, Malignant) 12/2018 - 08/2013
2	Inflammation (Inflammations) 01/2022 - 08/2007
2	Astrocytoma (Pilocytic Astrocytoma) 01/2019 - 07/2009
2	Acute Promyelocytic Leukemia 01/2018 - 05/2017
2	Necrosis 12/2007 - 08/2007
1	Liver Neoplasms (Liver Cancer) 11/2022
1	Fatty Liver 11/2022
1	Virus Diseases (Viral Diseases) 11/2022
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 11/2022
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022
1	Leukemia 01/2022
1	Chromosomal Instability (Chromosome Stability) 07/2021
1	Chromosome Aberrations (Chromosome Abnormalities) 07/2021
1	Triple Negative Breast Neoplasms 12/2018
1	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2018
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Wilms Tumor (Wilm's Tumor) 01/2018
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2018
1	Breast Neoplasms (Breast Cancer) 10/2014

Drug/Important Bio-Agent (IBA)

18	Temozolomide (Temodar)FDA LinkGeneric 03/2024 - 11/2004
14	DNA (Deoxyribonucleic Acid)IBA 03/2024 - 05/2002
7	Small Interfering RNA (siRNA)IBA 12/2018 - 12/2007
6	Proteins (Proteins, Gene)FDA Link 04/2019 - 11/2010
5	O(6)-Methylguanine-DNA MethyltransferaseIBA 01/2016 - 11/2010
4	O-(6)-methylguanineIBA 04/2022 - 01/2013
3	Irinotecan (Camptosar)FDA LinkGeneric 01/2022 - 01/2018
3	SurvivinIBA 07/2021 - 01/2010
3	MethyltransferasesIBA 04/2019 - 11/2010
3	Alkylating AgentsIBA 01/2019 - 12/2014
3	NimustineIBA 10/2015 - 12/2007
3	fotemustine (Muphoran)IBA 12/2014 - 11/2004
3	Cisplatin (Platino)FDA LinkGeneric 07/2009 - 12/2004
2	CarcinogensIBA 11/2022 - 12/2011
2	Lomustine (CCNU)FDA Link 01/2022 - 10/2014
2	Antineoplastic Agents (Antineoplastics)IBA 01/2022 - 01/2019
2	SenotherapeuticsIBA 01/2022 - 07/2021
2	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 07/2021 - 12/2007
2	Cytostatic AgentsIBA 04/2021 - 01/2019
2	IntegrinsIBA 12/2018 - 04/2017
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 10/2015
2	EnzymesIBA 01/2018 - 12/2011
2	Indicators and Reagents (Reagents)IBA 02/2017 - 01/2016
2	Environmental CarcinogensIBA 10/2013 - 08/2007
2	Messenger RNA (mRNA)IBA 08/2013 - 07/2012
2	GuanineIBA 11/2010 - 11/2004
2	Topotecan (Hycamtin)FDA LinkGeneric 01/2010 - 10/2005
1	fisetinIBA 03/2024
1	AflatoxinsIBA 11/2022
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2022
1	A-Form DNA (A-DNA)IBA 04/2022
1	Histones (Histone)IBA 04/2022
1	CarbamatesIBA 01/2022
1	Fluorouracil (Carac)FDA LinkGeneric 01/2022
1	devimistatIBA 01/2022
1	Tyrosine (L-Tyrosine)FDA Link 01/2022
1	venetoclaxIBA 07/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 04/2021
1	3-hydroxycholest-7-ene-14-carbaldehydeIBA 01/2021
1	Nitroso CompoundsIBA 01/2021
1	Tumor Suppressor Protein p53IBA 01/2019
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2019
1	Thioctic Acid (Lipoic Acid)IBA 01/2019
1	CilengitideIBA 12/2018
1	PoisonsIBA 12/2018
1	Vincristine (Oncovin)FDA LinkGeneric 12/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 12/2018
1	MicroRNAs (MicroRNA)IBA 01/2018
1	Proto-Oncogene Proteins c-bcl-2 (Proto Oncogene Proteins c bcl 2)IBA 01/2018
1	GlucocorticoidsIBA 01/2018
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2018
1	ran GTP-Binding ProteinIBA 01/2018
1	CaspasesIBA 01/2018
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2018
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2017
1	Caspase 3 (Caspase-3)IBA 04/2017
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 12/2016
1	Formaldehyde (Formol)FDA Link 01/2016
1	Caspase 9IBA 10/2015
1	Bcl-2-Like Protein 11IBA 10/2015
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 10/2015
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2015
1	VemurafenibIBA 12/2014
1	mafosfamideIBA 10/2014
1	exodeoxyribonuclease IIBA 08/2013
1	Exonucleases (3' 5' Exonuclease)IBA 08/2013
1	Complex MixturesIBA 08/2012
1	SmokeIBA 08/2012
1	Oncogene Proteins (Oncogene Protein)IBA 05/2011
1	DNA AdductsIBA 11/2010
1	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA 01/2010
1	Topoisomerase I InhibitorsIBA 01/2010

Therapy/Procedure

29	Therapeutics 03/2024 - 11/2004
5	Drug Therapy (Chemotherapy) 01/2022 - 11/2010
1	Chemoradiotherapy 05/2022
1	Precision Medicine 01/2018